V5 Ultimate
Ultimate
PricingResourcesCompany
Start free trial
HomeGlossaryBulk & tapped density (USP <616>)
Lab

Bulk & tapped density (USP <616>)

In short

Bulk and tapped density per USP <616> are the foundational powder characterisation tests for any supplement blend: bulk = mass / poured volume, tapped = mass / volume after 500/750/1250 mechanical taps. The ratio (and the derived Carr's compressibility index and Hausner ratio)...

Bulk and tapped density per USP <616> are the foundational powder characterisation tests for any supplement blend: bulk = mass / poured volume, tapped = mass / volume after 500/750/1250 mechanical taps. The ratio (and the derived Carr's compressibility index and Hausner ratio) predicts flow into capsule fillers and tablet press feed frames, drives the hopper/feeder design choice, and explains weight-variation failures at capsule fill or tablet compression long before they show up in 905.

Regulatory anchors
  • USP <616>
How V5 handles it
QMS — quality records next to the work they concern.
Deviations, corrective actions and quality review sit in the same system as production, so each quality record references the work order, step and lot it concerns.
Document control — one version in force, every change signed and explained.
Draft the next revision while the current one stays in use, approve it under your sign-off route, and track training on it — with the history kept.
Related terms
Carr's index & Hausner ratioCapsule Weight Control (100% Checkweighing)
Software that covers Bulk & tapped density (USP <616>)
V5 Ultimate Dietary Supplements
Written for supplement contract manufacturers and brand owners tired of surviving FDA 483s on paper.
Exploring software for this?

Try V5 free for 7 days with no card needed, or talk to our team about what applies to your operation.

Start free
Back to glossary

Next step

Try V5 with your own records, or ask a question first. Ask V5 opens with an editable question; nothing is sent until you choose to.

Start your free trial Browse all features
V5 Ultimate
Ultimate

Warehouse, quality and manufacturing software for regulated operations.

ProductIndustriesPricingResourcesSecurity & TrustCompanyLegal centre

© V5 Ultimate