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Carr's index & Hausner ratio

TL;DR

Carr's compressibility index ((tapped − bulk)/tapped × 100) and Hausner ratio (tapped/bulk) translate USP <616> density data into a powder flow class: Carr's <15 / Hausner <1.18 = free flowing; 15–20 / 1.19–1.25 = good; 21–25 / 1.26–1.34 = fair; >25 / >1.34 = poor and a glidan...

Carr's compressibility index ((tapped − bulk)/tapped × 100) and Hausner ratio (tapped/bulk) translate USP <616> density data into a powder flow class: Carr's <15 / Hausner <1.18 = free flowing; 15–20 / 1.19–1.25 = good; 21–25 / 1.26–1.34 = fair; >25 / >1.34 = poor and a glidant or wet granulation is needed. Most supplement weight-variation rejects trace to a blend whose Hausner ratio drifted above 1.34 after a raw-material lot change.

Regulatory anchors
  • USP <1174>
How V5 handles it
QMS — quality engineered into every action, not bolted on.
Because V5 owns the operator action, the QMS sees the data the second it’s captured — not at the end of the shift.
Document control with hard kiosk-level training enforcement.
Versioned SOPs are only useful if operators are actually trained on the current version. V5 enforces it at the kiosk.
Related terms
Bulk & tapped density (USP <616>)
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